o Liquid-Liquid extraction – basics and significance
o How do you choose a solvent to extract a compound that is already dissolved in another solvent?
o Equilibrium state of partition.
o How do you calculate the concentration of a compound dissolved in two immiscible solvents?
o Partition coefficient calculation. Know the equations. Does volume of solvents matter?
o Acid-Base extraction. Shifting the equilibrium by adding acid or base.
o How do you ionize / neutralize common functional groups? What acids / bases did you use in lab?
o Where do you use rotovap / filtration? Role of drying agent?
o Reason for increasing / decreasing the pH in terms of solubility.
o Extraction flowchart to separate a mixture of compounds.